Osimertinib(泰瑞沙)奥希替尼每次吃多少
病情描述:Osimertinib(泰瑞沙)奥希替尼每次吃多少
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病情描述:Osimertinib(泰瑞沙)奥希替尼每次吃多少
展开2024-03-04 12:53:37
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Osimertinib(泰瑞沙)奥希替尼每次吃多少,Osimertinib(Osimertinib)推荐剂量为每日80mg,直至疾病进展或出现无法耐受的毒性。
Osimertinib (Trade name: Tagrisso) is a targeted therapy drug that is used in the treatment of non-small cell lung cancer (NSCLC). Specifically, it is prescribed for patients with advanced NSCLC that has certain mutations in the epidermal growth factor receptor (EGFR) gene. This medication has shown promising results in improving outcomes for patients with this specific type of lung cancer. The dosage of Osimertinib may vary depending on several factors, including the patient's overall health, weight, and specific EGFR mutation status. Here, we will provide accurate information regarding the recommended dosage of Osimertinib.
1. The Recommended Dosage of Osimertinib:
The recommended dosage of Osimertinib is 80 milligrams (mg) once daily, taken orally with or without food. It is important to follow the prescribed dosage instructions given by your healthcare provider. Do not alter the dosage without consulting your doctor.
2. Factors Influencing Dosage:
The dosage of Osimertinib may be adjusted based on individual factors such as weight, kidney function, liver function, and other ongoing health conditions. Your healthcare provider will determine the appropriate dosage for you after considering these factors.
3. Compliance with Treatment:
To ensure the effectiveness of Osimertinib, it is crucial to take the medication exactly as prescribed by your doctor. Missing doses or altering the dosage without medical guidance may reduce its efficacy. If you have any concerns or experience difficulties with the prescribed dosage, talk to your healthcare provider for further guidance.
4. Possible Side Effects and Monitoring:
While Osimertinib is generally well-tolerated, some patients may experience side effects. Common side effects include diarrhea, skin rash, dry skin, nail changes, fatigue, decreased appetite, and respiratory symptoms such as cough and shortness of breath. Your doctor will monitor you for any potential side effects and may adjust the dosage or provide supportive care if needed. It is important to communicate any side effects you may experience to your healthcare team.
In conclusion, the recommended dosage of Osimertinib (Tagrisso) for the treatment of advanced non-small cell lung cancer with specific EGFR mutations is 80mg once daily. Adhering to the prescribed dosage and closely monitoring for any side effects can help maximize the benefits of this targeted therapy. As always, it is essential to consult with your healthcare provider for personalized advice and guidance regarding your specific treatment plan.
功能主治:一线治疗非小细胞肺癌EGFR抑制剂,改善生存且耐受良好
用法用量:剂量和给药 根据肿瘤或血浆样本中EGFR 外显子 19缺失或外显子21 L858R突变的存在,选择OYSIENDX(Osimertinib)奥希替尼转移性EGFR阳性NSCLC一线治疗的患者。如果在血浆样本中未检测到这些突变,则在可行的情况下测试肿瘤组织。 根据肿瘤或血浆样本中EGFR T790M突变的存在,在EGFR TKI治疗之后或之后选择OYSIENDX(Osimertinib)奥希替尼治疗转移性EGFR T790M突变阳性NSCLC的患者。建议仅在无法获得肿瘤活检的患者中检测血浆样本中是否存在T790M突变。如果在血浆样本中未检测到这种突变,则重新评估活组织检查在肿瘤组织检测中的可行性。 推荐的剂量方案 推荐剂量的OYSIENDX(Osimertinib)奥希替尼是每天一次80毫克片剂,直到疾病进展或不可接受的毒性。TAGRISSO(奥希替尼)可以带或不带食物。 如果错过了一剂奥希替尼,请不要弥补错过的剂量并按计划服用下一剂。 对难以吞咽固体的患者给药 仅在60 mL(2盎司)非碳酸水中分散片剂。搅拌直至片剂分散成小块(片剂不会完全溶解)并立即吞咽。在准备过程中不要挤压,加热或超声波。用120 mL至240 mL(4至8盎司)的水冲洗容器并立即饮用。 如果需要通过鼻胃管给药,将上述片剂分散在15 mL非碳酸水中,然后再用15 mL水将任何残留物转移到注射器中。所得的30mL液体应按照鼻胃管说明书进行,并进行适当的水冲洗(约30mL)。